Fig. 2: IgE Binding to Mast Cells and Basophils and Promoting an Inflammatory Response

The Fc portion of IgE is able to bind to receptors on mast cells and basophils. The cross-binding of antigens to the Fab portion of IgE triggers the release of inflammatory mediators. The resulting inflammatory response subsequently delivers defense cells and defense molecules from the bloodstream to the infection site.
Illustration of IgE Binding to Mast Cells and Basophils and Promoting an Inflammatory Response .jpg by Gary E. Kaiser, Ph.D.
Professor of Microbiology, The Community College of Baltimore County, Catonsville Campus
This work is licensed under a Creative Commons Attribution 4.0 International License.
Based on a work at https://cwoer.ccbcmd.edu/science/microbiology/index_gos.html.

Creative Commons License

Last updated: August, 2019
Please send comments and inquiries to Dr. Gary Kaiser